NutraBio | HMB

NutraBio HMB is a clinically proven ergogenic aid that has been shown in over 50 human studies to improve strength and power gains, increase lean mass, and aid recovery. HMB (short for beta-hydroxy beta-methylbutyrate) in an active metabolite of leucine that has both anticatabolic and anabolic properties.  Due to these attributes HMB reduces muscle protein breakdown while also inducing muscle protein synthesis. This means HMB can lead to rapid strength gains in less time, significantly increase lean muscle mass, support more complete muscle recovery, and reduce muscle damage from resistance exercise. In fact, a recent position stand by the International Society of Sports Nutrition validates these claims.  Based upon the comprehensive review of the HMB literature they concluded that HMB enhances muscle recovery by attenuating muscle damage; HMB increases muscle hypertrophy, strength, and power in trained and untrained populations when the appropriate exercise protocol is applied; HMB efficacy is manifested in young and old; and HMB is safe to consume.

Like creatine, beta-alanine and other well studied and proven performance enhancing compounds, NutraBio HMB makes a solid addition to any athletes training regimen and supplement stack. For example, research has shown when HMB is combined with creatine, the ergogenic benefits, as compared with what could otherwise be achieved by either compound independently, are significantly increased. Furthermore, you can rest assured that the HMB you are getting from NutraBio is an authentic, quality product as we source our HMB from Metabolic Technologies, who holds the use patents on HMB.  If your current HMB product doesn't have the Metabolic Technologies HMB logo on the label it is more than likely not HMB.

Quality and transparency. Science instead of hype. Results instead of disappointments. This is the NutraBio way. NutraBio is a name you can trust when it comes to clean and effective supplements.  Since 1996 we have been setting the quality standard in the world of sports nutrition.  Although the industry makes it seems like non-proprietary blends, proper dosing, and scientifically backed ingredients are something new; the fact is NutraBio pioneered this trend over two decades ago.  We have always been the innovators; not the imitators. 

With HMB, you make no sacrifices – you get proven and powerful muscle building and recovery benefits without the junk. HMB contains no fillers, excipients, proprietary blends, or other potentially unhealthy or unneeded additives. Only pure, 100% HMB which will support your body's ability to repair, recover, rebuild, and ultimately have you prepared to tackle your next training session.  

HOW EXACTLY DOES HMB WORK?

HMB's main physiological functions are its capacity to stabilize the cell membrane of muscles, stimulation of protein synthesis and decrease of protein breakdown. The mechanism is related to HMB's role as an alternate substrate for cholesterol synthesis. The inhibition of cholesterol synthesis results in impaired muscle functions, increased muscular damage and finally, muscular necrosis. In order to maintain membrane integrity, muscle cells rely on cholesterol synthesis. Increased intramuscular HMB may provide readily available substrate for the synthesis of cholesterol needed to form and stabilize the muscle cell membrane. HMB has been shown to up-regulate muscle synthesis by the activation of the mTOR pathway, and to decrease muscle breakdown by influencing the ubiquitin-proteasome dependent pathways of protein degradation.  Simply put HMB shifts the balance of protein synthesis, tipping the scale in muscle's favor. When protein synthesis equals protein breakdown, there is no net gain of muscle protein. This is important in maintaining/increasing strength. Therefore, the increase in protein synthesis and decrease in protein breakdown achieved through HMB supplementation results in greater strength gains and faster recovery via net gains in muscle protein.

HOW DOES HMB STACK UP SCIENTIFICALLY?

HMB has been extensively studied in athletes, alone and in combination with other supplements (such as creatine), as an adjunct to exercise to help improve body composition, strength, and performance. More than 50 human clinical studies, 20 review articles and two meta-analyses published in peer reviewed journals have demonstrated HMB's effectiveness in increasing lean body mass, strength, decreasing markers of muscle damage and reducing muscle soreness. Furthermore, HMB's benefits have been demonstrated in trained and untrained individuals, men and women, ranging from young adults to seniors.  Let's take a brief look at a few key studies that demonstrates HMB's ergogenic effects.